She has a wealth of experience, having worked in major medical institutions such as "Ss. Cyril and Methodius" Children's University Hospital in Skopje, North Macedonia. In addition, she has practiced in Tirana, Albania, in "Queen Geraldine" Obstetric and Gynecological University Hospital", as well as in "Hygea" Hospital, where she worked in the Department of Pediatrics. After gaining experience in these top-tier private hospitals, she established her own private clinic.

As for foreign languages, she speaks them very well. English, Italian, Greek, French and Macedonian. Dr. Persefoni brings a broad, multicultural perspective to her practice, providing high-quality care to patients of diverse backgrounds.